Cookies help us deliver our services. By using our services, you agree to our use of cookies.

Does animal protein shorten our life span? With James Clement

James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the last two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School and has received international press coverage. Through worldwide scientific collaborations and in his own laboratory, James focuses on advancing cutting-edge biomedical discoveries. He is the founder of the nonprofit Betterhumans biomedical research organization. Led by a collection of high-profile researchers, the organization focuses on bringing cutting edge scientific discoveries from the lab to the clinic. Clement was the 12th person in the world to have his whole genome sequenced and is Personal Genome Project participant #145

Service: YouTube
Publshed on: Jan 14, 2020
Duration: 01:58:57
Channels
Fundamental Health with Paul Saladino, MD


Segments
Start of podcast
10:36 to 11:15
39 seconds
What type of research is James doing and how does it relate to aging?
11:16 to 13:20
2.1 minutes
Compression of morbidity.
13:21 to 24:15
10.9 minutes
Feedlot meat and processed foods (24:16-25:01)
24:16 to 26:15
2.0 minutes
Super centenarian studies.
26:16 to 29:16
3.0 minutes
Observations on what super centenarians have in common.
29:17 to 32:05
2.8 minutes
Laron Dwarfs and IGF1 (32:36-33:11)
32:06 to 33:55
1.8 minutes
Should we over stimulate IGF1?
33:56 to 37:35
3.7 minutes
Measuring IGF1
37:36 to 40:05
2.5 minutes
Blue Zones and centenarian diets
40:06 to 43:15
3.2 minutes
Intermittent Hypoxia
43:16 to 47:05
3.8 minutes
Over fasting, finding a good balance.
47:06 to 52:05
5.0 minutes
Environmental hormesis
52:06 to 53:15
1.2 minutes
Okinawans
53:16 to 56:05
2.8 minutes
Confounding variables.
56:06 to 01:00:50
4.7 minutes
mTor/ketosis and glycogen depletion in the liver.
01:00:51 to 01:04:05
3.2 minutes
Animal based diets and intermittent ketosis.
01:04:06 to 01:06:35
2.5 minutes
James' thoughts on the carnivore diet.
01:06:36 to 01:11:20
4.7 minutes
Lack of nutrients in a plant based diet.
01:11:21 to 01:12:55
1.6 minutes
Benefits of prolonged ketosis in morbidly obese.
01:12:56 to 01:16:35
3.7 minutes
Protein sparing modified fast benefits.
01:16:36 to 01:20:35
4.0 minutes
Calorie restricted pure vegan diet.
01:20:36 to 01:22:25
1.8 minutes
Dexa scan.
01:22:26 to 01:26:15
3.8 minutes
James's insulin levels.
01:26:16 to 01:28:05
1.8 minutes
AGEs (advanced glycation end products)
01:28:06 to 01:35:35
7.5 minutes
Stress and glucose levels.
01:35:36 to 01:39:15
3.7 minutes
Does too much protein harm the kidneys?
01:39:16 to 01:45:35
6.3 minutes
Protein cycling.
01:45:36 to 01:46:59
1.4 minutes
Occasional long term fasting benefits.
01:47:00 to 01:48:00
1.0 minutes
Loma Linda sperm quality.
01:48:01 to 01:50:05
2.1 minutes
Carnivore diet for longevity.
01:50:06 to 01:52:45
2.7 minutes
Issues with studies comparing meat eaters vs. non meat eaters.
01:52:46 to 01:54:25
1.7 minutes
The most radical thing James has done recently.
01:54:26 to N/A
4.5 minutes